Walk Around Wales

Progressive supranuclear palsy (PSP) is a degenerative neurological disorder of uncertain etiology characterized by gait ataxia, slowing or inability to generate voluntary saccadic eye movements, and axial rigidity. The most characteristic aspect of PSP is an inability to move the eyes, but the first symptom of PSP is usually unsteadiness and falling.

PSP was first described as a distinct disorder in 1964. It is sometimes referred to as Steele-Richardson-Olszewksi, or "SRO", syndrome, from the names of the individuals who defined the disorder. Although PSP is rare and has no treatment, it has attracted an immense amount of research activity since being discovered, and there are thousands of papers on this obscure condition.

		Brynhyfryd is a residential street in the south Wales town of Glynneath. To the north of the street is an industrial waste landfill site. Of the 62 houses in the street, 17 have a border with or partial border with the former landfill site. Of those 16 houses 3 of the occupants have died from rare neurological disorders, two of those disorders were idenitical, progressive supranuclear palsy occurred in a group of 5 houses bordering the site at the point where the Cuddy Group was most active. The only previous instance of a cluster of PSP cases is in a northern French town with a background of heavy industry. A paper studying the instances of PSP in the town states that: "Wattrelos is a town in northern France where textile dyeing plants and tanneries operated for most of the 20th century, using arsenic and chromate from the nearby chemical plants. Arsenic and hexavalent chromium contamination have been documented in the soils of the sites of former plants in Wattrelos and Leers,24 where the cluster of PSP cases described in this report live." The previous owners of the site Cuddy Group Ltd ended tipping at the site in 2016, the Cuddy Group contracts leading up this point included demolition and waste management at Zeon Chemicals (formerly BP Sully), BP Llandarcy, British Steel, Llanwern & British Steel, Port Talbot, all sites believed to be contaminated extensively. Eyewitness reports by residents bordering the site at Brynhyfryd place barrels of unknown waste there along with several reports of asbestos tipping. The suggested causes of the PSP deaths in Wattrelos according to the paper submitted to the American Academy of Neurology by some of the world's leading experts in PSP states that Arsenic from industrial waste is the most likely cause of the PSP cases while chromium has also been described as a potential cause. Both arsenic and chromium have both been found at the former Cuddy site bordering Brynhyfryd.
2/5/22		Simon Knoyle correspondence with Dr Golbe. (source Peter Allen) not known if complete Add email info about the definition of a cluster that I sent to Golbe following this note.
20230515R-BKRS-NNTA-2001-fooled	PSP Huw Morris	"For most people probability is about what may happen in the future, not events in the observed past. An event that has already taken place has 100% probability, ie certainty" Fooled by Randomness: The Hidden Role of Chance in Life and in the Markets is a book by Nassim Nicholas Taleb published by Texere (ISBN 1-58799-071-7) https://youtu.be/eV7SupmEgFs - YouTube @ 1.24.54